Mark | Date Date | Title Title | |||
---|---|---|---|---|---|
No. 314 | 19 Dec 2019 |
International Best Practices for Identification of Priorities within Chemicals Management Systems
This document captures and examines schemes used internationally for prioritising chemicals for risk assessment and/or risk management, and identifies commonalities, differences, lessons learned and areas for improvement. Based on this analysis it... |
|||
No. 311 | 22 Oct 2019 |
Guiding Principles and Key Elements for Establishing a Weight of Evidence for Chemical Assessment
This document is intended to provide universal Guiding Principles that should be considered when developing or augmenting systematic approaches to Weight of Evidence (WoE) for chemical evaluation and Key Elements to formulating a systematic approach... |
|||
No. 298 | 13 Jun 2019 |
Guiding Principles on Good Practices for the Availability/Distribution of Protected Elements in OECD Test Guidelines
This document describes good practices for the licensing of protected elements included in OECD Test Guidelines (TGs). Transparency and communication are needed around protected elements resulting from innovation in sciences and techniques that are... |
|||
No. 297 | 07 Feb 2019 |
Customisation Opportunities of IUCLID for the Management of Chemical Data
The IUCLID (International Uniform ChemicaL Information Database) can be customised to manage chemical data in different contexts and is a platform employing globally harmonised data elements pertinent to chemicals. The version 6 of IUCLID software... |
|||
No. 296 | 06 Dec 2018 |
Considerations for Assessing the Risks of Combined Exposure to Multiple Chemicals
The report outlines the technical aspects of the various approaches and methodologies available with respect to the assessment of risks from combined exposures to multiple chemicals. The document draws from approaches applied and experience gained in... |
|||
No. 286 | 10 Dec 2018 |
Guidance Document on Good In Vitro Method Practices (GIVIMP)
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing,... |
|||
No. 263 | 25 Jul 2019 |
Second Edition - Guidance Document on Integrated Approaches to Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation
This document suggests an Integrated Approach on Testing and Assessment (IATA) for serious eye damage and eye irritation hazard identification. The document also provides key information characteristics of each of the individual information sources... |
|||
No. 260 | 10 Mar 2017 |
Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA)
The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there... |
|||
No. 259 | 13 Apr 2017 |
Guidance on the Incorporation of Bioavailability Concepts for Assessing the Chemical Ecological Risk and/or Environmental Threshold Values of Metals and Inorganic Metal Compounds
Several models, tools and methods have been published in the past 20 years to include bioavailability in risk assessment and several OECD member countries already have developed frameworks and published guidance documents for taking metal... |
|||
No. 256 | 11 Jul 2017 |
Guidance Document on the Reporting of Defined Approaches and Individual Information Sources to be Used within Integrated Approaches to Testing and Assessment (IATA) for Skin Sensitisation
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides guidance on the reporting of defined approaches to testing... |
|||
No. 255 | 13 Apr 2017 |
Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to... |
|||
No. 250 | 13 Apr 2017 |
Report on Considerations from Case Studies on Integrated Approaches for Testing and Assessment (IATA) - First Review Cycle (2015)
OECD member countries have been making efforts to expand the use of alternative methods in assessing chemicals. The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and... |
|||
No. 238 | 13 Apr 2017 |
Overview on genetic toxicology TGs
Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to... |
|||
No. 237 | 13 Apr 2017 |
Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests
Acute toxicity tests are an area of focus for developing alternative assays and approaches to address animal welfare concerns. In the context of this document, acute toxicity studies refer to studies involving a single exposure to a test chemical and... |
|||
No. 230 | 13 Apr 2017 |
OECD Guidance for Characterising Hydrocarbon Solvents for Assessment Purposes
This document presents a harmonized method for characterising, for assessment purposes, a specific subcategory of UVCBs (Substances of Unknown or Variable composition, Complex reaction products or Biological materials): hydrocarbon solvent... |
|||
No. 229 | 13 Apr 2017 |
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches... |
|||
No. 215 | 13 Apr 2017 |
Report of the Workshop on a Framework for the Development and Use Of Integrated Approaches to Testing and Assessment
This document is a report of the Workshop on a framework for the development and use of integrated approaches to testing and assessment which was held on 17-19 November 2014 in Crystal City VA, USA. This framework should provide guiding principles,... |
|||
No. 212 | 13 Apr 2017 |
Guidance on Selecting a Strategy for Assessing the Ecological risk of Organometallic and Organic Metal Salt Substances based on their Environmental Fate
In this document a strategy is presented to facilitate the ecological risk assessment of organometallic compounds (OM) and organic metal salts (OMS), outlining key steps that are based on elucidation of the fate of these substances in the... |
|||
No. 211 | 13 Apr 2017 |
Guidance Document for Describing Non-Guideline In Vitro Test Methods
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the... |
|||
No. 207 | 11 Jul 2014 |
New Scoping Document on in vitro and ex vivo Assays for the Identification of Modulators of Thyroid Hormone Signalling
This scoping document aims at bringing forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, to provide recommendations for their development/use, and also, to identify aspects/blocks of the thyroid... |
OECD Series on Testing and Assessment
This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).
English
- ISSN: 20777876 (online)
- https://doi.org/10.1787/20777876
1 - 20 of 78 results
International Best Practices for Identification of Priorities within Chemicals Management Systems
OECD
19 Dec 2019
This document captures and examines schemes used internationally for prioritising chemicals for risk assessment and/or risk management, and identifies commonalities, differences, lessons learned and areas for improvement. Based on this analysis it...
Guiding Principles and Key Elements for Establishing a Weight of Evidence for Chemical Assessment
OECD
22 Oct 2019
This document is intended to provide universal Guiding Principles that should be considered when developing or augmenting systematic approaches to Weight of Evidence (WoE) for chemical evaluation and Key Elements to formulating a systematic approach...
Guiding Principles on Good Practices for the Availability/Distribution of Protected Elements in OECD Test Guidelines
OECD
13 Jun 2019
This document describes good practices for the licensing of protected elements included in OECD Test Guidelines (TGs). Transparency and communication are needed around protected elements resulting from innovation in sciences and techniques that are...
The IUCLID (International Uniform ChemicaL Information Database) can be customised to manage chemical data in different contexts and is a platform employing globally harmonised data elements pertinent to chemicals. The version 6 of IUCLID software...
The report outlines the technical aspects of the various approaches and methodologies available with respect to the assessment of risks from combined exposures to multiple chemicals. The document draws from approaches applied and experience gained in...
Guidance Document on Good In Vitro Method Practices (GIVIMP)
OECD
10 Dec 2018
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing,...
Second Edition - Guidance Document on Integrated Approaches to Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation
OECD
25 Jul 2019
This document suggests an Integrated Approach on Testing and Assessment (IATA) for serious eye damage and eye irritation hazard identification. The document also provides key information characteristics of each of the individual information sources...
Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA)
OECD
10 Mar 2017
The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there...
Several models, tools and methods have been published in the past 20 years to include bioavailability in risk assessment and several OECD member countries already have developed frameworks and published guidance documents for taking metal...
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides guidance on the reporting of defined approaches to testing...
Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment
OECD
13 Apr 2017
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to...
Report on Considerations from Case Studies on Integrated Approaches for Testing and Assessment (IATA) - First Review Cycle (2015)
OECD
13 Apr 2017
OECD member countries have been making efforts to expand the use of alternative methods in assessing chemicals. The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and...
Overview on genetic toxicology TGs
OECD
13 Apr 2017
Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to...
Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests
OECD
13 Apr 2017
Acute toxicity tests are an area of focus for developing alternative assays and approaches to address animal welfare concerns. In the context of this document, acute toxicity studies refer to studies involving a single exposure to a test chemical and...
This document presents a harmonized method for characterising, for assessment purposes, a specific subcategory of UVCBs (Substances of Unknown or Variable composition, Complex reaction products or Biological materials): hydrocarbon solvent...
Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations
OECD
13 Apr 2017
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches...
Report of the Workshop on a Framework for the Development and Use Of Integrated Approaches to Testing and Assessment
OECD
13 Apr 2017
This document is a report of the Workshop on a framework for the development and use of integrated approaches to testing and assessment which was held on 17-19 November 2014 in Crystal City VA, USA. This framework should provide guiding principles,...
Guidance on Selecting a Strategy for Assessing the Ecological risk of Organometallic and Organic Metal Salt Substances based on their Environmental Fate
OECD
13 Apr 2017
In this document a strategy is presented to facilitate the ecological risk assessment of organometallic compounds (OM) and organic metal salts (OMS), outlining key steps that are based on elucidation of the fate of these substances in the...
Guidance Document for Describing Non-Guideline In Vitro Test Methods
OECD
13 Apr 2017
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the...
New Scoping Document on in vitro and ex vivo Assays for the Identification of Modulators of Thyroid Hormone Signalling
OECD
11 Jul 2014
This scoping document aims at bringing forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, to provide recommendations for their development/use, and also, to identify aspects/blocks of the thyroid...